Wegovy® 7.2 mg Dose: Benefits, Results, Side Effects & Eligibility

Wegovy 7.2 mg is the highest-strength dose of semaglutide currently available for medical weight loss in the UK. Designed for adults who need additional support beyond standard doses, it can help deliver greater, more sustained weight-loss results when used alongside lifestyle changes. 

This guide explains how Wegovy 7.2 mg works, who it’s for, expected results, side effects, and whether it may be right for you. 

What Is Wegovy 7.2 mg? 

Wegovy is a once-weekly injectable medication containing semaglutide, a GLP-1 receptor agonist that helps regulate appetite and calorie intake. 

The 7.2 mg dose is a higher maintenance option introduced for people who: 

• Have not reached desired weight-loss results on 2.4 mg 

• Experience weight-loss plateaus 

• Have a higher starting BMI 

It builds on the same proven mechanism as lower doses but offers enhanced clinical efficacy for suitable patients. 

How Does Wegovy 7.2 mg Work? 

Wegovy mimics the naturally occurring hormone GLP-1, which helps to: 

• Reduce hunger signals in the brain 

• Increase feelings of fullness 

• Slow stomach emptying 

• Reduce cravings and snacking 

This leads to lower calorie intake and supports long-term weight management when combined with a balanced diet and regular physical activity. 

Wegovy 7.2 mg Weight-Loss Results 

Clinical Trial Evidence 

In phase 3 clinical studies, including the STEP UP trial, patients using Wegovy 7.2 mg achieved: 

• Average weight loss of around 20–21% 

• Greater reductions compared with the 2.4 mg dose 

• Higher likelihood of achieving ≥15% and ≥20% weight loss 

These outcomes make Wegovy 7.2 mg one of the most effective prescription weight-loss treatments available in the UK. 

Who Is Eligible for Wegovy 7.2 mg? 

You may be eligible if you are: 

• Aged 18 or over 

• Have a BMI of 30 or higher, or 

• Have a BMI of 27 or higher with weight-related health conditions such as: 

• High blood pressure 

• High cholesterol 

• Type 2 diabetes 

• Sleep apnoea 

A clinical assessment is required to confirm suitability. 

How Is Wegovy 7.2 mg Taken? 

Wegovy is taken as a once-weekly injection. 

Patients typically: 

1. Start on a lower dose 

1. Increase gradually over several weeks 

1. Move to a maintenance dose 

At present, the 7.2 mg dose may be delivered by combining three 2.4 mg injections once weekly, depending on prescribing guidance, until dedicated pens become widely available. 

Wegovy 7.2 mg Side Effects 

Side effects are similar to other GLP-1 medications and are usually mild to moderate, especially during dose increases. 

Common Side Effects 

• Nausea 

• Vomiting 

• Diarrhoea 

• Constipation 

• Stomach pain 

• Fatigue 

• Headache 

Less Common but Noted at Higher Doses 

• Skin sensitivity or tingling sensations (dysaesthesia) 

• Increased gastrointestinal discomfort 

Most side effects improve as your body adjusts. Medical advice should be sought if symptoms are severe or persistent. 

Is Wegovy 7.2 mg Safe? 

Wegovy has undergone extensive clinical testing and is approved for weight management in the UK. 

It may not be suitable if you: 

• Have type 1 diabetes 

• Have a history of pancreatitis 

• Have certain thyroid conditions 

• Are pregnant or breastfeeding 

Your clinician will review your medical history before prescribing. 

Do You Need Monitoring on Wegovy 7.2 mg? 

Yes. Ongoing clinical support helps ensure: 

• Safe dose progression 

• Side effects are managed 

• Weight loss remains healthy and sustainable 

Wegovy works best as part of a clinically supported weight-loss plan that includes nutrition, activity, and behavioural guidance. 

Is Wegovy 7.2 mg Right for You? 

Wegovy 7.2 mg may be suitable if you: 

• Have already tried lower doses 

• Want enhanced weight-loss results 

• Are committed to long-term lifestyle change 

• Qualify following a medical assessment 

A healthcare professional can help determine the most appropriate dose for your needs. 

Frequently Asked Questions About Weygovy 7.2mg

How much weight can you lose on Wegovy 7.2 mg? 

Clinical trials show average weight loss of around 20–21% of starting body weight. 

Is Wegovy 7.2 mg available in the UK? 

Yes, it will be  available through approved UK providers following a clinical assessment. It is currently being made available through the supply chain and should be available soon 

Is Wegovy 7.2 mg better than 2.4 mg? 

For some people, yes — especially those who experience weight-loss plateaus or need additional support. 

Can Weygovy side effects be worse at 7.2 mg? 

Side effects may be slightly more frequent, but most are manageable and temporary. There are patients who may try the higher dose and find the side effects are too significant who will need to return to the lower dose. This is okay and will not lead to long term issues but there may be a period of washout where you will have to manage side effects. As always, drinking plenty of water can help reduce these and over the counter medications can help.  

The weight loss achieved in trials of the new dose is equivalent to that achieved by using the highest dose of Mounjaro. But with all medications the aim is to take the minimum dose where you avoid side effects but achieve your weight loss goals.  

Remember that changing habits is just as important for long term weight loss so medication is just one of the supporting products and for long term healthy weight maintenance other changes will be required so that when you taper down to a maintenance dose you are able to maintain your weight loss.